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Description
Human ATRX , His tagProduct Specification Species Human Synonyms Transcriptional regulator ATRX, ATP dependent helicase ATRX, X linked helicase II, X linked nuclear protein (XNP), Znf HX, RAD54L, XH2 Accession P46100 Amino Acid Sequence Protein sequence(P46100, Gly2250 Asn2450, with C 10*His)
Product Specification
| Species | Human |
| Synonyms | Transcriptional regulator ATRX, ATP-dependent helicase ATRX, X-linked helicase II, X-linked nuclear protein (XNP), Znf-HX, RAD54L, XH2 |
| Accession | P46100 |
| Amino Acid Sequence | Protein sequence(P46100, Gly2250-Asn2450, with C-10*His) MGYHEHDSLLDHKEEEELTEEERKAAWAEYEAEKKGLTMRFNIPTGTNLPPVSFNSQTPYIPFNLGALSAMSNQQLEDLINQGREKVVEATNSVTAVRIQPLEDIISAVWKENMNLSEAQVQALALSRQASQELDVKRREAIYNDVLTKQQMLISCVQRILMNRRLQQQYNQQQQQQMTYQQATLGHLMMPKPPNLIMNPSNGGGGSHHHHHHHHHH |
| Expression System | E.coli |
| Molecular Weight | Theoretical:24.9kDa Actual:27kDa |
| Purity | ＞95% by SDS-PAGE |
| Endotoxin | <1EU/μg |
| Tag | His Tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | Lyophilized from a 0.2 μm filtered solution of 0.2M PBS, pH7.4. |
| Reconstitution | Reconstitute no more than 1 mg/mL according to the size in deionized water after rapid centrifugation. |
| Stability & Storage | 12 months from date of receipt, -20 to -70 °C as supplied. 6 months, -20 to -70 °C under sterile conditions after reconstitution. 1 week, 2 to 8 °C under sterile conditions after reconstitution. Please avoid repeated freeze-thaw cycles. |
Background
Transcriptional regulator ATRX also known as ATP-dependent helicase ATRX, X-linked helicase II, or X-linked nuclear protein (XNP) is a protein that in humans is encoded by the ATRX gene. It contains an ATPase / helicase domain, and thus it belongs to the SWI/SNF family of chromatin remodeling proteins. ATRX is required for deposition of the histone variant H3.3 at telomeres and other genomic repeats. These interactions are important for maintaining silencing at these sites. Acquired mutations in ATRX have been reported in a number of human cancers including pancreatic neuroendocrine tumours, gliomas, astrocytomas, osteosarcomas, and malignant pheochromocytomas. There is a strong correlation between ATRX mutations and an Alternative Lengthening of Telomeres (ALT) phenotype in cancers.
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4.1 ★★★★★
Based on 986 reviews
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Product Reviews
★★★★★ 5
Excelente
Excelente la uso hace años.❤️
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Reviewed in the United States on April 26, 2026
★★★★★ 1
Strong irritating scent
Strong perfume scent that triggered my allergies. Why would a product designed for sensitive skin have fragrance added? My dermatologist had provided me some samples from Avene that were unscented and worked great, but this product is unusable for me if it's perfumed.
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Reviewed in the United States on January 7, 2026
★★★★★ 5
Skin care
This lotion works great. I use the balm for my elbows and shoulders
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Reviewed in the United States on April 19, 2026
★★★★★ 5
Good product, good value
This is a nice set of Vaseline products. I had never heard of the balm stick and I am so glad that I tried it. It works great on my itchy eyelids. I have been using the lotion for many years, in one formulation or another, but the yellow variety since the 70's. It works so nice after getting some sun and it smells good. Then there is the old fashioned Vaseline in a jar. Always need that on hand. The combination set was a good value.
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Reviewed in the United States on February 23, 2022
★★★★★ 5
Excelente producto
Gran producto hidrata la piel adecuadamente
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Reviewed in the United States on April 21, 2026
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