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Description
FCAR/CD89 His Tag Protein, HumanProduct Specification Species Human Synonyms Immunoglobulin Alpha Fc Receptor; IgA Fc Receptor; CD89; FCAR Accession P24071 1 Amino Acid Sequence Gln22 Asn227, with C terminal His Expression System HEK293 Molecular Weight 42 55 kDa(Reducing) Purity 95%, by SDS PAGE under reducing conditions Endotoxin <0. 1EU g Conjugation Unconjugated Tag His Tag Physical Appearance Lyophilized Powder Storage Buffer PBS, pH7. 4 Reconstitution Reconstitute at less than
Product Specification
| Species | Human |
| Synonyms | Immunoglobulin Alpha Fc Receptor; IgA Fc Receptor; CD89; FCAR |
| Accession | P24071-1 |
| Amino Acid Sequence | Gln22-Asn227, with C-terminal His |
| Expression System | HEK293 |
| Molecular Weight | 42-55 kDa(Reducing) |
| Purity | ＞95%, by SDS-PAGE under reducing conditions |
| Endotoxin | <0.1EU/μg |
| Conjugation | Unconjugated |
| Tag | His Tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | PBS, pH7.4 |
| Reconstitution | Reconstitute at less than 1 mg/mL according to the size in ultrapure water after rapid centrifugation . |
| Stability & Storage | · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles. |
Background
FCAR, also known as Fc alpha RI or CD89, is a 50-100 kDa glycosylated bone marrow-specific type I transmembrane (TM) Fc receptor, which is a member of the immunoglobulin gene superfamily. FCAR exists on the surface of myeloid cells such as neutrophils, monocytes, macrophages and eosinophils, and mediates the immune response to pathogens. It interacts with IgA-regulated targets and triggers a variety of immune defense processes, including phagocytosis, antibody-dependent cell-mediated cytotoxicity and stimulating the release of inflammatory mediators. This product is made by recombinant expression of human FCAR from HEK293 cell line, purified, sterilized, filtered, packaged and freeze-dried.
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Exchange/Return Notes
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