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Description
S-RMab® CD163 Recombinant Rabbit mAb (SDT-R164)Product Specification Host Rabbit Antigen CD163 Synonyms M130, Hemoglobin scavenger receptor Immunogen N A Location Secreted, Cell membrane Accession Q86VB7 Clone Number SDT R164 Antibody Type Recombinant mAb Application WB, IHC P, IP, IF Reactivity Hu, Ms, Rt Purification Protein A Concentration 0. 25 mg ml Tag N A Physical Appearance Liquid Storage Buffer PBS, 40% Glycerol, 0. 05% BSA, 0. 03% Proclin 300 Stability & Storage 12 months from date of
Product Specification
| Host | Rabbit |
| Antigen | CD163 |
| Synonyms | M130, Hemoglobin scavenger receptor |
| Immunogen | N/A |
| Location | Secreted, Cell membrane |
| Accession | Q86VB7 |
| Clone Number | SDT-R164 |
| Antibody Type | Recombinant mAb |
| Application | WB, IHC-P, IP, IF |
| Reactivity | Hu, Ms, Rt |
| Purification | Protein A |
| Concentration | 0.25 mg/ml |
| Tag | N/A |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:500 | null |
| IHC-P | 1:1000-1:2000 | null |
| IF | 1:2000 | null |
| IP | 1:25 | null |
Background
CD163 is a monocyte/macrophage specific marker expressed predominantly on cells which possess strong anti-inflammatory potential. The expression of CD163 is strongly induced by anti-inflammatory mediators such as glucocorticoids and interleukin-10, while being inhibited by pro-inflammatory mediators such as interferon-gamma. CD163-expressing mononuclear phagocytes, as well as soluble CD163, may both take part in downregulating an inflammatory response [PubMed: 22038213].
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