SKU: 36752187974

Biotinylated IL-21R Fc&Avi Tag Protein, Human

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Description

Biotinylated IL-21R Fc&Avi Tag Protein, HumanProduct Specification Species Human Synonyms IL21R,CD360,NILR,CD360 antigen,CD360,IL 21 receptor,interleukin 21 receptor,interleukin 21 receptor Accession Q9HBE5 1 Amino Acid Sequence Cys20 Pro236 with Fc&Avi Tag at the C Terminus Expression System HEK293 Molecular Weight 65 80kDa (Reducing) Purity 95% by SDS PAGE ;> 85% SEC HPLC Conjugation Biotin Tag Avi Tag Physical Appearance Lyophilized Powder Storage Buffer PBS, PH7. 4, 5% trehalose

Product Specification


Species Human
Synonyms IL21R,CD360,NILR,CD360 antigen,CD360,IL-21 receptor,interleukin 21 receptor,interleukin-21 receptor
Accession Q9HBE5-1
Amino Acid Sequence

Cys20-Pro236 with Fc&Avi Tag at the C-Terminus
Expression System HEK293
Molecular Weight

65-80kDa (Reducing)
Purity ＞95% by SDS-PAGE ;> 85% SEC-HPLC
Conjugation Biotin
Tag Avi Tag
Physical Appearance Lyophilized Powder
Storage Buffer

PBS, PH7.4, 5% trehalose
Reconstitution

Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
Stability & Storage

· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. 
· 3 months, -20 to -80℃ under sterile conditions after reconstitution.
· 1 week, 2 to 8℃ under sterile conditions after reconstitution.  
· Please avoid repeated freeze-thaw cycles.
Reference

1.Yan L, Zhang J, Guo D, Ma J, Shui SF, Han XW. [Corrigendum] IL‑21R functions as an oncogenic factor and is regulated by the lncRNA MALAT1/miR‑125a‑3p axis in gastric cancer. Int J Oncol. 2025 Sep;67(3):74.
He Y, Zheng X, Dang Z, Hao X, Liu Y, Wang P, Chen Y, Wang Y, Sha W. Association of T-Cell Profiles With Disease Severity, Drug-Induced Liver Injury, and Treatment Completion in Tuberculosis. Clin Respir J. 2025 Aug;19(8):e70114.

Background

Interleukin-21 receptor (IL21R) is also known as CD antigen CD360, Novel interleukin receptor (NILR), is a receptor for interleukin-21 and belongs to the type I cytokine receptor family or type 4 subfamily. Mature human IL-21 R consists of a 213 amino acid (aa) extracellular domain (ECD) with 4 conserved cysteine residues, a fibronectin type III domain, and a WSxWS motif, followed by a 21 aa transmembrane domain and a 285 aa cytoplasmic domain with a Box 1 motif, a kinase domain, and several sites for tyrosine phosphorylation . Within the ECD, human IL-21 R shares 69% aa identity with mouse and rat IL-21 R, respectively. IL21R transduces the growth promoting signal of IL21, and is important for the proliferation and differentiation of T cells, B cells, and natural killer (NK) cells.

Shipping Notes
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Exchange/Return Notes
  • We offer a 30-day return/exchange service after receiving.
  • Final sale items are not eligible for returns or exchanges.
  • To process your return/exchange, please contact us at [email protected]
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SKU: 36752187974

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4.8 ★★★★★
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ShAmZ
Fort Morgan, US
★★★★★ 5
Good alternative to traditional gums- no aspartame no artificial coloring.
Flavor Name: Spearmint, Size: 55 Count (Pack of 1)
Love this gum, no aspartame, no artificial coloring and good taste, you get used to chewing it for a long time, the taste goes away little faster than traditional gums but I don't care
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 28, 2026
G
Verified Purchase
Gianni Breck
Louisville, US
★★★★★ 5
Great Xylitol Chewing Gum!
Flavor Name: Spearmint, Size: 55 Count (Pack of 3), Flavor Name: Spearmint, Size: 55 Count (Pack of 3)
This review is for PUR Gum | Aspartame Free Chewing Gum | 100% Xylitol | Natural Spearmint Flavored Gum, 55 Pieces (Pack of 3). I got 2 of the 3-pack at the time because it was cheaper to do so than to get a 6-pack. Of course, the next day the 6-pack was cheaper lol. Anyway, this is great xylitol gum and not overly expensive like Zellie’s. I take 2 (which is one serving meaning 2g of xylitol) after “most” meals because it’s supposed to be good for my oral health. I chew one piece at a time for a couple minutes to prolong the sweet flavor instead of popping both into my mouth together. I like chewing these because they don’t harden up like some gums do. They stay soft throughout and I often forget and chew them for 15-20 minutes at a time. Anyway, I did the math and compared the PUR gum to other 100% xylitol gums out there and this one was a clear winner to me for the same benefits. I would totally recommend this gum and I like that it’s aspartame free! I’d give it a 5.0/5.0 - 03/20/2026.
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Reviewed in the United States on March 20, 2026
A
Verified Purchase
Asha77
Phoenix, US
★★★★★ 3
Great taste but cannot use
Flavor Name: Spearmint, Size: 55 Count (Pack of 1)
First time trying for dental care. Really enjoy the taste only drawback taste doesn’t last long. However, it’s better than other sugar substitutes which my stomach does not like. Glad I signed up for the three pack sub. Great product! Recommend. May 16, 2026 Update: Unfortunately I cannot use this product after the initial trial every time I chew on these i experience stomach issues so the three pack I purchased will need to find someone that can use them or throw out.
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Reviewed in the United States on May 6, 2026
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Verified Purchase
OpinBook
Phoenix, US
★★★★★ 5
Powerful lasting peppermint flavor & the xylitol fights plaque!
Flavor Name: Spearmint, Size: 55 Count (Pack of 6)
The gum has a powerful peppermint taste – very refreshing. The flavor lasts a long time. The main reason that I bought this gum is because it has 100% xylitol. Xylitol helps fight plaque buildup. I have only had the product one day, so I can't say that it works, but I read many reports before I bought the gum that xylitol is excellent for fighting plaque buildup. It also has no sugar. It's vegan and it has only five calories per two pieces. I have so far only chewed one piece at a time. One piece seems plenty for me. I've read that people need from six to ten grams of xylitol per day to effectively fight plaque. So, this gum needs to be chewed accordingly. Many people chew after every time they eat. I am happy with this purchase.
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Reviewed in the United States on May 12, 2026
C
Verified Purchase
C. Critchfield
Fort Morgan, US
★★★★★ 5
Only protein shake I've found that doesn't cramp my stomach
Flavor Name: Chocolate, Size: 14 Fl Oz (Pack of 12)
I've tried the vanilla, strawberry and chocolate, and chocolate is by far the best. It's not too sweet (where as the vanilla and strawberry were). It doesn't have any extra whey concentrate or caseinate or soy or whatever added to it to boost protein. Brands that do that mess up my stomach, giving me bad stomach cramps. This is just highly filtered milk, and lactase enzyme that tackles the lactose sugar left behind after filtration. Maybe that's the secret. (I can drink normal milk and not get cramps. But, whey protein isolate and other things give me cramps.) This has become a go-to in a protein diet I'm on. I'll have one for breakfast with some coffee. That lasts me until lunch. If not, I'll simply have another 2 hours later. They're each less than 200 calories, so it's not too bad having another if it staves off hunger. I find I eat a smaller lunch. I might have another one for a mid-afternoon snack. Then I'll have a normal dinner. Basically I'm replacing bigger meals and a breakfast with 2-3 smaller calorie protein shakes. And the protein keeps me satisfied. (unlike something like slim fast that's just all sugar and ramps up your insulin). They're a bit pricey (almost $4/bottle). But, I'm cutting back on my grocery bill as well. So, it's balancing out. I figure I could be spending $12/day on fast food or some other garbage that makes me fat. Instead I'm drinking 2-3 of these a day, and am down 10lbs over a month. I'll stick with these.
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Reviewed in the United States on April 27, 2026

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