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Description
Human CSF1R, His tagProduct Specification Species Human Synonyms CSF 1 receptor (CSF 1 R; CSF 1R; M CSF R), Proto oncogene c Fms, CD115, FMS Accession P07333 Amino Acid Sequence Protein sequence(P07333, Ile20 Asn320, with C 10*His)
Product Specification
| Species | Human |
| Synonyms | CSF-1 receptor (CSF-1-R; CSF-1R; M-CSF-R), Proto-oncogene c-Fms, CD115, FMS |
| Accession | P07333 |
| Amino Acid Sequence | Protein sequence(P07333, Ile20-Asn320, with C-10*His) IPVIEPSVPELVVKPGATVTLRCVGNGSVEWDGPPSPHWTLYSDGSSSILSTNNATFQNTGTYRCTEPGDPLGGSAAIHLYVKDPARPWNVLAQEVVVFEDQDALLPCLLTDPVLEAGVSLVRVRGRPLMRHTNYSFSPWHGFTIHRAKFIQSQDYQCSALMGGRKVMSISIRLKVQKVIPGPPALTLVPAELVRIRGEAAQIVCSASSVDVNFDVFLQHNNTKLAIPQQSDFHNNRYQKVLTLNLDQVDFQHAGNYSCVASNVQGKHSTSMFFRVVESAYLNLSSEQNLIQEVTVGEGLNGGGGSHHHHHHHHHH |
| Expression System | HEK293 |
| Molecular Weight | Theoretical:34.6kDa Actual:50kDa |
| Purity | ＞95% by SDS-PAGE |
| Endotoxin | <1EU/μg |
| Tag | His Tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | Lyophilized from a 0.2 μm filtered solution of 0.2M PBS, 1mM EDTA, pH7.4. |
| Reconstitution | Reconstitute no more than 1 mg/mL according to the size in deionized water after rapid centrifugation. |
| Stability & Storage | 12 months from date of receipt, -20 to -70 °C as supplied. 6 months, -20 to -70 °C under sterile conditions after reconstitution. 1 week, 2 to 8 °C under sterile conditions after reconstitution. Please avoid repeated freeze-thaw cycles. |
Background
Colony stimulating factor 1 receptor (CSF1R), also known as macrophage colony-stimulating factor receptor (M-CSFR), and CD115 (Cluster of Differentiation 115), is a cell-surface protein encoded by the human CSF1R gene (known also as c-FMS). CSF1R is a receptor that can be activated by two ligands: colony stimulating factor 1 (CSF-1) and interleukin-34 (IL-34). CSF1R is highly expressed in myeloid cells, and CSF1R signaling is necessary for the survival, proliferation, and differentiation of many myeloid cell types in vivo and in vitro. CSF1R signaling is involved in many diseases and is targeted in therapies for cancer, neurodegeneration, and inflammatory bone diseases.
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4.6 ★★★★★
Based on 296 reviews
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Product Reviews
★★★★★ 5
Thumbs up.
Color: White, Size: Medium
Looks great, fits well and comfortable.
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Reviewed in the United States on May 18, 2026
★★★★★ 4
Fine little tight around collar
Color: White, Size: X-Large
Little tight around collar
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Reviewed in the United States on April 20, 2026
★★★★★ 5
Great
Color: Light Blue, Size: XX-Large
Great dress shirt !!
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Reviewed in the United States on April 28, 2026
★★★★★ 5
Highly Recommended Dress Shirt
Fit Type: Regular Fit, Color: White, Size: Medium
Honestly, I Love It. Fits Great, Neck Isn't Too Tight Like Most Shirts, And It's Comfortable. It Is 100% Cotton, So Dont Forget To Iron It Before Wearing It. High Quality Dress Shirt. Highly Recommended.
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Reviewed in the United States on October 21, 2025
★★★★★ 5
Surprisingly good shirt for the price
Fit Type: Regular Fit, Color: White, Size: XX-Large
I’m generally pleased with my purchase. I got a 2XL because the website it would fit my neck. Around the waist it fit similar to Amazon Essentials work shirts (like mechanics use which I find comfortable).
It was snug around the waist when sitting, but I can’t complain because I have a belly. I did find the neck snug when buttoning the top button so it means the neck is 18 or 18.5 and I wear a 19/19.5 to have 1-2 fingers space in the collar.
The shirt is surprisingly thick like Amazon’s work shirts, much thicker than other dress shirts from another brand.
And I am pleased that this shirt has button holes like other Amazon shirts does, all vertical button holes except the last one at the bottom which is horizontal. That feature keeps the shirt from unbuttoning itself during daily movement at the office. A very nice feature! I was a little disappointed in how it was packaged however but I have to press and wash it anyway.
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Reviewed in the United States on February 24, 2023